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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-20b
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs), human embryonic kidney cell line HEK293
Methods qRT-PCR, luciferase reporter assay, Western blot
Expression pattern down-regulated
Functional description miR-20b is important for the regulation of VEGF-mediated changes in HRECs and rat retinal tissues under hyperglycemic conditions possibly via targeting AKT3.
PubMed ID 27421659
Year 2016
Title MiR-20b targets AKT3 and modulates vascular endothelial growth factor-mediated changes in diabetic retinopathy.
Drug-related ncRNA NO

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